Non-stationary forward flux sampling.
نویسندگان
چکیده
We present a method, Non-Stationary Forward Flux Sampling, that allows efficient simulation of rare events in both stationary and non-stationary stochastic systems. The method uses stochastic branching and pruning to achieve uniform sampling of trajectories in phase space and time, leading to accurate estimates for time-dependent switching propensities and time-dependent phase space probability densities. It is suitable for equilibrium or non-equilibrium systems, in or out of stationary state, including non-Markovian or externally driven systems. We demonstrate the validity of the technique by applying it to a one-dimensional barrier crossing problem that can be solved exactly, and show its usefulness by applying it to the time-dependent switching of a genetic toggle switch.
منابع مشابه
Processing of Non-Stationary Signal Using Level-Crossing Sampling
The spectral characteristics of multimedia signals typically vary with time. Preferably, the sampling density of them would comply with instantaneous bandwidth of signal. The paper discusses the level-crossing sampling principle, which provides such capability for analog-to-digital conversion. As the captured samples are spaced non-uniformly, the appropriate digital signal processing is require...
متن کاملEstimation of Induction Motor Speed by EKF In Stationary Frame and Use of Rotor Flux and Study of Parameter Variations
متن کامل
Estimation of Induction Motor Speed by EKF In Stationary Frame and Use of Rotor Flux and Study of Parameter Variations
متن کامل
Optimum Pareto design of vehicle vibration model excited by non-stationary random road using multi-objective differential evolution algorithm with dynamically adaptable mutation factor
In this paper, a new version of multi-objective differential evolution with dynamically adaptable mutation factor is used for Pareto optimization of a 5-degree of freedom vehicle vibration model excited by non-stationary random road profile. In this way, non-dominated sorting algorithm and crowding distance criterion have been combined to differential evolution with fuzzified mutation in order ...
متن کاملTransition path sampling and forward flux sampling. Applications to biological systems.
The last decade has seen a rapid growth in the number of simulation methods and applications dealing with the sampling of transition pathways of rare nanoscale events. Such studies are crucial, for example, for understanding the mechanism and kinetics of conformational transitions and enzymatic events associated with the function of biomolecules. In this review, a broad account of transition pa...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- The Journal of chemical physics
دوره 136 17 شماره
صفحات -
تاریخ انتشار 2012